Archive for May 11th, 2018

Combating the deadly gastrointestinal infection C. diff

Clostridium difficile infection is the most common cause of antibiotic-associated diarrhea in developed countries. Researchers have discovered how the C. diff toxin B recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells and lead to deadly gastrointestinal infections. The findings could pave the way for new C. diff antitoxins and also show […]

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Reducing tapeworm infection could improve academic performance, reduce poverty

Tapeworm infection from eating contaminated pork can damage the brain, causing learning impairments and possibly enforcing cycles of poverty. A new study is the first to look at infection rates within schools and propose solutions targeting children. Source: Reducing tapeworm infection could improve academic performance, reduce poverty

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Beyond killing tuberculosis

Historically, our view of host defense against infection was that we must eliminate pathogens to eradicate disease. However, this perspective has recently been challenged as scientists have taken a lesson from plant biologists about an ancient strategy involving the ability to ‘tolerate’ rather than ‘resist’ infection to maintain health. This concept, referred to as ‘disease […]

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Conventional view of opioid mechanism of action upended in new study

A new discovery shows that opioids used to treat pain, such as morphine and oxycodone, produce their effects by binding to receptors inside neurons, contrary to conventional wisdom that they acted only on the same surface receptors as endogenous opioids, which are produced naturally in the brain. Source: Conventional view of opioid mechanism of action […]

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