When neurons are out of shape, antidepressants may not work

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD. Now, researchers have discovered differences in growth patterns of neurons of SSRI-resistant patients. The work has implications for depression […]

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How does estrogen protect bones? Unraveling a pathway to menopausal bone loss

Women who have reached menopause are at a greater risk of developing osteoporosis, which can lead to bone fractures and long-term impairment of mobility. Studies have suggested a link between reduced bone density and low estrogen levels due to menopause, but the basis for this link is unclear. Researchers found that the protein Sema3A plays […]

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Sleep problems, Alzheimer's disease are linked, but which comes first?

A new article explores the pathophysiological factors that link sleep disturbances and Alzheimer’s disease. Better understanding of this connection may lead to potential diagnostics and therapeutics for Alzheimer’s disease, and other neurodegenerative diseases and dementia. Source: Sleep problems, Alzheimer's disease are linked, but which comes first?

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