Proteins cooperate to break up energy structures in oxygen starved heart cells

Researchers found that the filamin A-Drp1 complex mediates mitochondrial fission in a mouse model of hypoxic heart cells. Results show that hypoxic stress brought about the interaction of filamin A with Drp1 and increased Drp1 activity in heart cells. This process led to mitochondrial fragmentation and cell senescence. Further investigation demonstrated that the drug cilnidipine […]

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So, you think you're good at remembering faces, but terrible with names?

The cringe-worthy experience of not being able to remember an acquaintance’s name leads many of us to believe we are terrible with names. However, new research has revealed this intuition is misleading; we are actually better at remembering names than faces. Source: So, you think you're good at remembering faces, but terrible with names?

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Synthetic DNA-delivered antibodies protect against Ebola in preclinical studies

Scientists have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical models. Study results showed that DMAbs were expressed over a wide window of time and offered complete and long-term protection against lethal virus challenges. DMAbs may also provide a novel powerful platform for rapid screening of monoclonal antibodies […]

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Earlier treatment could help reverse autistic-like behavior in tuberous sclerosis

New research in a mouse model suggests that the drug rapamycin can reverse autism-like social deficits — but only if given early. The study is the first to shed light on the crucial timing of therapy to improve social impairments in a condition associated with autism spectrum disorder. Its findings could help inform future clinical […]

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