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Research uncovers previously unknown effects of fasting, including notably increased metabolic activity and possible anti-aging effects. Source: Fasting ramps up human metabolism, study shows
Continue Reading →A male mouse identifies the sex of an unfamiliar mouse because of hard-wired brain physiology, not previous experience, investigators have found. Source: Male mice hard-wired to recognize sex of other mice
Continue Reading →Melanoma is the deadliest form of skin cancer and notorious for its resistance to conventional chemotherapy. Approximately 25 percent of melanoma is driven by oncogenic mutations in the NRAS gene, making it a very attractive therapeutic target. However, despite decades of research, no effective therapies targeting NRAS have been forthcoming. Source: Method to 'turn off' […]
Continue Reading →Melanoma is the deadliest form of skin cancer and notorious for its resistance to conventional chemotherapy. Approximately 25 percent of melanoma is driven by oncogenic mutations in the NRAS gene, making it a very attractive therapeutic target. However, despite decades of research, no effective therapies targeting NRAS have been forthcoming. Source: Method to 'turn off' […]
Continue Reading →Scientists have uncovered molecules released by invasive skin cancer that reprogram healthy immune cells to help the cancer to spread. Source: Skin cancer can spread in mice by hijacking the immune system
Continue Reading →In a new study, researchers shed new light on the origin and function of hormone producing cells in the intestine and open new avenues to tweak gut hormone production to treat human disease. Source: Tweaking hormone-producing cells in the intestine
Continue Reading →Visualizing how some patients successfully fought off deadly coronaviruses could pave the way to combat these respiratory infections, new research suggests. Source: An unexpected mode of action for an antibody
Continue Reading →Researchers studying p53, the heralded cancer-fighting ‘guardian of the genome,’ found that the human protein also plays a role in promoting tumors, in addition to suppressing them. They found that the PUMA protein works inside the cell’s mitochondria to switch energy production processes and stimulate cancer growth. Source: Opposite effect: Protein widely known to fight […]
Continue Reading →Researchers revealed that the immune cells basophils caused emphysema in mice with COPD-like features induced by intranasal administration of elastase. They showed that basophils, previously linked mainly to allergies and fighting parasites, initiated a cascade of reactions eventually leading to the release of excess MMP-12 and the destruction of alveolar walls. The team hopes that […]
Continue Reading →In a context of overuse of insecticides, which leads to the selection of resistant mosquitoes, it is already known that this resistance to insecticides affects interactions between mosquitoes and the pathogens they transmit. Researchers demonstrate that mechanisms of insecticide resistance, observed in Culex quinquefasciatus vector, impact the transmission of West Nile virus. Source: Insecticide resistance […]
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