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Researchers have detailed a mechanism that sets the stage for the fate decision that gives rise to two major subsets of effector cells: T follicular helper cells and non-T follicular helper cells, known as Tfh and non-Tfh cells. Source: Immune response mechanism described for fate determination of T cells
Continue Reading →Researchers have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the US Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen […]
Continue Reading →Sleeping sickness-causing parasites contain an unusual protein synthesis machinery. A team of researchers has resolved its very special structure for the first time. Source: A very special protein synthesis machinery
Continue Reading →Researchers have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth. The analysis of thousands of brain cells isolated from mice offers researchers a high-resolution map that enables scientists to view the detailed genomic changes cells undergo as the cerebellum wires […]
Continue Reading →Astrocytes’ important role in brain function suggests they are also involved in disease. Now, scientists have identified an astrocyte subpopulation as the dominant cell type to spring into action in vivo in a neuroinflammatory disease setting. Source: Malicious brain cell identified
Continue Reading →Scientific and medical institutions must fundamentally reconsider how they address sexual harassment in the workplace, experts argue in a new article. Source: Scientific institutions continue to lag behind the #TimesUp movement
Continue Reading →Scientific and medical institutions must fundamentally reconsider how they address sexual harassment in the workplace, experts argue in a new article. Source: Scientific institutions continue to lag behind the #TimesUp movement
Continue Reading →Leptospirosis infections, caused by Leptospira bacteria, occur in people and animals around the world, but different strains of the bacteria may vary in their ability to cause disease and to jump between species. Now, researchers have for the first time described the characteristics of the Leptospira variants that infect cattle in Uruguay. Source: Leptospirosis strains […]
Continue Reading →New insights into how Kaposi’s sarcoma-associated herpesvirus induces genome instability and promotes cell proliferation could lead to the development of novel antiviral therapies for KSHV-associated cancers. Source: How a virus destabilizes the genome
Continue Reading →A type of immune cell that produces a protein called CD4 plays an important role in protecting mice infected with the Zika virus against severe neurological disease, according to a new study. Source: How the immune system protects against Zika-induced neurological symptoms
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