Archive for September, 2018
Researchers have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the US Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen […]
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Sleeping sickness-causing parasites contain an unusual protein synthesis machinery. A team of researchers has resolved its very special structure for the first time. Source: A very special protein synthesis machinery
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Researchers have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth. The analysis of thousands of brain cells isolated from mice offers researchers a high-resolution map that enables scientists to view the detailed genomic changes cells undergo as the cerebellum wires […]
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Astrocytes’ important role in brain function suggests they are also involved in disease. Now, scientists have identified an astrocyte subpopulation as the dominant cell type to spring into action in vivo in a neuroinflammatory disease setting. Source: Malicious brain cell identified
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Scientific and medical institutions must fundamentally reconsider how they address sexual harassment in the workplace, experts argue in a new article. Source: Scientific institutions continue to lag behind the #TimesUp movement
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Scientific and medical institutions must fundamentally reconsider how they address sexual harassment in the workplace, experts argue in a new article. Source: Scientific institutions continue to lag behind the #TimesUp movement
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Leptospirosis infections, caused by Leptospira bacteria, occur in people and animals around the world, but different strains of the bacteria may vary in their ability to cause disease and to jump between species. Now, researchers have for the first time described the characteristics of the Leptospira variants that infect cattle in Uruguay. Source: Leptospirosis strains […]
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New insights into how Kaposi’s sarcoma-associated herpesvirus induces genome instability and promotes cell proliferation could lead to the development of novel antiviral therapies for KSHV-associated cancers. Source: How a virus destabilizes the genome
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A type of immune cell that produces a protein called CD4 plays an important role in protecting mice infected with the Zika virus against severe neurological disease, according to a new study. Source: How the immune system protects against Zika-induced neurological symptoms
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Much remains unknown about a group of individuals known as HIV post-treatment controllers, including how rare this ability is. Two new studies explore the characteristics of this group as well as the biological mechanisms that may help explain this unique ability. Source: Largest study of 'post-treatment controllers' reveals clues about HIV remission
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