Archive for March 18th, 2020

Using 'organs-on-a-chip' to model complicated diseases

Biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system on a microfluidic chip seeded with human cells. With this ‘organs-on-a-chip’ model, they could explore the role of immune cells in ulcerative colitis and other inflammatory diseases. Source: Using 'organs-on-a-chip' to model complicated diseases

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Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal ‘firing’ in the central nervous system and for brain and heart function. These channels use a ”ball-and-chain” mechanism to help regulate their ion flow, according to a new study. Source: Ball-and-chain inactivation of ion channels visualized […]

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New technique 'prints' cells to create diverse biological environments

With the help of photolithography and programmable DNA, researchers have created a new technique that can rapidly ‘print’ two-dimensional arrays of cells and proteins that mimic a wide variety of cellular environments in the body. This technique could help scientists develop a better understanding of the complex cell-to-cell messaging that dictates a cell’s final fate. […]

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Maggot analysis goes molecular for forensic cases

Maggots on a dead body or wound can help pinpoint when a person or animal died, or when maltreatment began in elder, child care or animal neglect cases. However, the current process for making this determination is time consuming and resource intensive. It also relies on species assessment by trained entomologists. Now, researchers report the […]

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